Policies, Procedures and Guidelines

Continuing Review Policy

Created 05/28/2019

Policy Statement

Continuing review of USDA species protocols must be completed annually. PHS funded studies must be reviewed once every three years. The IACUC will complete more frequent continuing review if required by the funding agency supporting the animal use protocol (Department of Defense, VA, etc.).

If the required continuing review is not completed, the protocol will expire and all animal use activities must stop.

Procedures

Investigators will be notified before the first and second anniversary of the original protocol approval when continuing review is required. Review forms are available in the electronic protocol submission system and must be submitted, reviewed, and approved before the anniversary date.

The IACUC completes the continuing review via the Designated Member Review (DMR) Process.

If the continuing review is not approved by the anniversary date, the IACUC office will notify the Principal Investigator and the Division of Comparative Medicine that animal use must cease until further notice. If a protocol is allowed to lapse while the associated vertebrate animals are housed on campus, the animals must be transferred to the DCM holding protocol, transferred to another study, placed with an outside agency, or euthanized. The Attending Veterinarian, or designee, will evaluate the animals and take appropriate action if the protocol expiration poses any threat to animal welfare.

Once the PI has successfully submitted and obtained approval of the continuing review, the protocol will be reactivated and animal work will be permitted to continue.

References and applicable regulations

PHS Policy requires the IACUC to conduct continuing review of each previously approved, ongoing activity covered by PHS Policy at appropriate intervals as determined by the IACUC, including a complete review in accordance with the PHS Policy IV.C.1-4 at least once every three years. For USDA covered species, continuing review of activities are required not less than annually 9 CFR 2.31(c)(1)-(8).

Download the Continuing Review Policy (PDF).