Grab a drink, attend a talk, meet other innovators, and make things happen.
Thursday, January 16th, 2020
4:30 – 5:30 p.m.
@4240 Duncan Avenue
Havana Room, 2nd Floor
The Institute of Clinical and Translational Sciences (ICTS) Precision Medicine team invites you to an on-going collaboration with Venture Café. These sessions will be hosted on the third Thursday of every month in the @4240 building.
“Healthspan therapeutics that increase the ratio of “young” to “old” genes.”
Tim R. Peterson, PhD
Assistant Professor of Medicine and Genetics
As our global population lives longer, there is increasing interest in healthspan – the period of life that one is free from aging-associated conditions, such as Alzheimer’s and osteoporosis. Healthspan is recognized as important because of its impact on quality of life and health care costs. We’ve developed a healthspan metric we call the “Y/O Ratio” based on genes we’ve categorized as either “young” or “old”. We applied our metric to identify potential anti-aging drugs with a Y/O Ratio greater than 1. In the coming months we will test these drugs in mouse models of Alzheimer’s, which is a prevalent aging condition with limited treatment options.
“Achieving Productive Aging: Understanding the systemic regulation of aging and longevity in mammals and developing an anti-aging intervention”
Shin-ichiro Imai, MD, PhD
Professor of Developmental Biology
I will introduce the cutting-edge front of aging/longevity research in our lab, focusing on the inter-tissue communications among the hypothalamus, skeletal muscle, and adipose tissue. I will also talk about our efforts of translating our preclinical results to humans and developing an anti-aging intervention using an NAD intermediate called nicotinamide mononucleotide (NMN).
For more information visit the ICTS Precision Medicine website.