The BioBank core provides specimens (blood, resection and endoscopic biopsy specimens, stool) and clinical data collected from patients with gastrointestinal diseases. The core maintains a database of clinical and genetic information linked to the specimens to accelerate clinical translational studies in human gastrointestinal diseases.
The mission of this core is to act as a nidus promoting clinical-translational and basic research on human gastrointestinal diseases. The core maintains an open IRB approved protocol that allows for collection of specimens and longitudinal clinical data from patients with gastrointestinal diseases and control populations and sharing of these specimens and information with DDRCC members. This protocol allows the core to maintain a database of clinical information linked to specimens and data obtained from these specimens, thus accelerating clinical-translational and basic research in gastrointestinal diseases. The core staff members enroll target patient populations, collect specimens and clinical data, process and store specimens, and maintain the database of clinical information. Specimens collected and processed by the core currently include blood, surgical resections, endoscopic biopsies, and stool. The bio-bank core can partner with other core facilities to simplify and accelerate downstream analysis of collected specimens for investigators. The core also routinely performs genotype analysis on enrolled patients and can perform microarray analysis on RNA isolated from specimens if requested by investigators. The bio-bank core presently contains clinical data, specimens, and genotype analysis from over 2000 patients with gastrointestinal disease and control patients. Pre-existing clinical data and tissue specimens are available to DDRCC investigators to support their investigations. In addition the core can partner with investigators to initiate new collections of specimens and/or clinical data to further expand this database. Current collections include specimens from individuals with inflammatory bowel disease, irritable bowel syndrome, hereditary colon cancer, and controls. DDRCC members can access an excel file containing de-identified baseline demographics of the enrolled patient population via a secure link to facilitate study designs using this core. Investigators who wish to use the core to support their investigations should submit a one page description of the proposed study to Dr. Newberry (firstname.lastname@example.org). Proposals will be evaluated by executive members of the DDRCC and selected based upon their relevance to the mission of the DDRCC.
Service available to All entities, including for-profit organizations.
Priority service for All entities, including for-profit organizations.
Access is limited to members of the Digestive Disease Research Center Cores at Washington University
- Human tissues and derivatives including DNA, RNA, and serum.
- -80 Freezers
- -150 C Freezers
Please contact this core directly for pricing information.
Digestive Disease Research Core Center (DDRCC)