The Optical Imaging Core (OIC), part of the Molecular Imaging Center, provides access to state-of-the-art optical imaging instruments for conducting studies ranging from live cells to in vivo animals. A highly successful team of NIH funded researchers, scientists and technicians under the leadership of Dr. Samuel Achilefu is available to discuss and provide support in conducting molecular imaging studies.

Our priority is to provide support to NIH funded researchers making important contributions to cancer research. The Optical Imaging Core is available to the Washington University community, as well as other institutions and private partners.

Our imaging resources include:

  • In-vivo and ex-vivo small animal and live cell fluorescence and bioluminescence imaging systems
  • Optical 2D planar, 3D tomographic, optoacoustic, Xray/CT, and fluorescence lifetime imaging resources

    Visit the Optical Radiology Lab’s website for more information and the instruments’ applications

Core Description

We strive to provide high quality support for expediting molecular imaging studies and research.

In Vivo Animal Imaging 

Faculty: Dr. Samuel Achilefu  (

This core includes:

  • IVIS SpectrumCT and IVIS 50 In Vivo Bioluminescence (BLI) and Fluorescence Imaging Systems (BLI) for 2D and 3D applications
  • Perkin Elmer FMT 4000 small animal fluorescence diffuse optical tomography (DOT) system
  • Optix MX3– time-domain Diffuse Optical Imaging system, with a tunable laser excitation wavelength and filter sets for fluorescence lifetime (FLT) imaging
  • Bruker Multispectral FX Pro fluorescence imaging  system with X-ray source and RAD PADD radiographic imaging module for digital radiography and planar scintigraphy.


Service available to All entities, including for-profit organizations.

Priority service for Specific groups, centers or departments – see Additional Information for details.

Additional information:

Siteman Cancer Center : Members receive subsidized rates.  

The Optical Imaging Core is a fee based core facility. Consultation with the OIC management is required before using this facility.  All users must clarify with their laboratory PI regarding the User Fees prior to commencing studies in the facility. To discuss a project or obtain additional information, please email Julie Prior at


  • Small animal fluorescence imaging using the IVIS SpectrumCT, Bruker, Optix, and FMT systems
  • Technical support for small animal imaging studies
  • Small animal bioluminescence imaging (BLI) with IVIS imaging systems
  • Technical support for analysis of imaging data
  • Bioluminescence and fluorescence measurement of live cells in well plates


  • PerkinElmer IVIS SpectrumCT In Vivo Bioluminescence and fluorescence Imaging System for 2D and 3D in vivo imaging
  • Xenogen/Caliper/PerkinElmer IVIS 50 - In Vivo Bioluminescence Imaging System (BLI) - provides sensitive and quantitative bioluminescent imaging
  • ART Optix MX3- time-domain Diffuse Optical Imaging system, tunable laser excitation wavelength and filter sets for fluorescence lifetime (FLT) imaging
  • PerkinElmer FMT 4000 small animal fluorescence DOT system
  • Bruker Multispectral FX Pro system- multi-modal imaging, diverse excitation & emission channels for fluorescence imaging


Please contact this core directly for pricing information.

Molecular Imaging Center
Siteman Cancer Center (SCC)