The Siteman Biostatistics Shared Resource (SBSR) facility is a shared resource core supporting consultation on biostatistics and epidemiology. The facility supports cancer research through experimental designs, study monitoring and data analyses. The faculty and staff has a wide array of expertise (ranging from clinical trial design, survival analysis, diagnostic test, predictive modeling, causal inference, electronic health record data analysis) and utilize efficient methods that reflect the “best practices” in biostatistics and epidemiology. Examples of SBSR core work include: NIH-funded peer reviewed cancer grants and pilot and small-scale studies to become part of successful applications for peer-reviewed funding. To request SBSR services, complete the Service Request Form. If first time user, please see the tutorial for iLab account registration here [PDF].
Core Description
Leadership Core Director: Graham A Colditz, MD, DrPH Core Co-Director: Jingqin Rosy Luo, PhD.
The Siteman Biostatistics Shared Resource (SBSR) facility is a shared resource core supporting consultation on biostatistics and epidemiology. The facility supports cancer research through experimental designs, study monitoring and data analyses. The faculty and staff utilize efficient methods that reflect the “best practices” in biostatistics and epidemiology. Examples of SBSR core work include: NIH-funded peer reviewed cancer grants and pilot and small-scale studies to become part of successful applications for peer-reviewed funding.
To request SBSR services, complete the Service Request Form. If first time user, please see the tutorial for iLab account registration here [PDF].
Washington University Co-Authorship Guidelines apply. An author is considered to be an individual who has made substantial intellectual contributions to a scientific investigation.
In order to better manage statistical work on projects with external deadlines, the SBSR core requires that the faculty and staff:
- Be informed of new P01 and SPORE grant submissions at least 6 months before the deadline;
- Be informed of new R01 and K series grant submissions at least 1 month before the deadline;
- Be provided with data sets for an analysis for an abstract submission (e.g., for ASCO, AACR, ASH, ASTRO) at least 1 month before the deadline;
- Will only work on analysis and reporting for abstract presentations (e.g., for ASCO, AACR, ASH, ASTRO meetings) if the Core was notified at the time of abstract submission and the relevant statistician was given enough time to comment on the abstract at the time of submission
Access
Service available to All entities, including for-profit organizations.
Priority service for No distinctions.
Additional information:
Accessible for all
Services
- Clinical trials. The Siteman Biostatistics Shared Resource (SBSR) core consults on and reviews all clinical protocols activated by the SCC
- Epidemiologic and population-based studies and studies in somatic genetics and the risk of cancer
- Experiments in the biology of cancer, including genomic experiments and laboratory and animal studies
- Translational research studies with combined measurements on clinical and biological parameters
- Advice and support in the preparation of grant applications of SCC members
- Scientific computing for data analysis and scientific graphics necessary for analyses of epidemiological, clinical, basic science and genomic studies
- Advice and consultation to the Quality Assurance Office for Clinical Trials (QACT) on efficient and accurate database design and management of clinical research data
- Computer support for the clinical research database
- Education for members of Siteman Cancer Center in the areas of study design, data collection, computerization, and statistical methods for laboratory, clinical and population based studies
Equipment
- SBSR manages data through RedCap or onCore for cancer related trials and studies
- SBSR utilizes state of the art statistical software R, Rstudio, SAS for statistical analysis on PC and on computing servers
- SBSR uses PASS and other R and SAS existing packages and functions for power calculation, as well as via conducting simulation
Pricing
Pricing is subject to core verification
The Siteman Biostatistics Shared Resource (SBSR) provides services using three mechanisms:
(1) Pre-award grant preparation: free of charge
Effective September 1st, 2016, the Siteman Biostatistics Shared Resource will be subsidizing all work related to the preparation of new cancer grant applications. Principal Investigators will not be charged for any support needed to develop new projects for their cancer grant application.
Principal Investigators are encouraged to include statistical support in their grant and study budgets.
(2) Percentage efforts sourced to grants
No subsidy will be available for post-award grant support. Statistician can be budgeted on grants to provide services.
(3) Hourly billing
All post-award support not sourced will be charged to the Principal Investigator at the full published rates (below) by service hours.
All researchers will receive 1 hour of free consultation for any cancer project not related to grant preparation. All projects initiated prior to 9/1/2016 will be billed at the rates below.
The Siteman Biostatistics Shared Resource (SBSR) core operates as fee-for-service facility. Standard fees for the core are: $105/hour for faculty advisement and $70/hour for staff advisement.
Complete the Service Request Form to begin the process.
To better assist our researchers in working with the Siteman Biostatistics Shared Resource, the shared resource core has introduced several new policies and procedures below.
• All requests will be submitted through a short online request form
• Just-In-Time (JIT) funding is available to investigators who utilize SBSR
• Fee-for-service agreements are required for billable requests
Below are several funding sources available to investigators. Please take the applications seriously.
American Cancer Society Institutional Research Grant (annually, 4 awards at $30,000)
Ongoing Siteman Cancer Center opportunities (announced as cycles open with turnaround time of 6 months)
Internal competitions
There are designated internal competitions for junior faculty within the Washington University system. Make sure you qualify based on the foundations’ requirements. Please contact Leah Giannakis Goldsmith, 314-454-8981, with any questions regarding internal funding opportunities.
Mallinckrodt Scholar Program
Supports mid-career investigators engaged in basic biomedical research that has the potential to significantly advance the understanding, diagnosis or treatment of disease. Assistant professors and associate professors in the fifth to eighth year of their tenure track are eligible. The award is not intended for faculty who have already achieved the rank of full professor. Faculty may hold an R01 when they apply for the Mallinckrodt Scholars program. The Scholar Award provides $100,000 per year for a period of four years.
Faculty members without established funding for their project are encouraged to apply for Just-In-Time (JIT) funding through the ICTS. Visit the JIT website for details.
AFFILIATIONS
Siteman Cancer Center (SCC)