The Small-Animal Magnetic Resonance (MR) Facility provides state-of-the-art facilities and infrastructure for magnetic resonance imaging and spectroscopy of mice, rats and other small laboratory animals. Located in the heart of the Washington University Medical Center, the Small-Animal MR Facility combines instrumental and intellectual capabilities found at few other institutions and serves a broad community of scientists who have a pressing need for quantitative MR image analysis of small laboratory animal model systems.
Core Description
The Small-Animal MR Facility provides access to and maintenance of small-animal MR scanners and ancillary facilities and routinely assists and trains researchers in imaging and spectroscopy procedures and data analysis methods. In addition to supporting research applications of small-animal MR imaging, the Facility also provides research and development at the frontier of MR imaging technology in an effort to make the most powerful new imaging strategies available to its community of users. The ancillary small-animal research services and capabilities provided by the Facility are extraordinary. Support resources include consultation for experiment planning and data analysis, animal-procedure assistance for maintenance and monitoring of physiologic status during imaging, and informatics support for local and remote data access, analysis, visualization, and archival.
Access
Service available to All entities, including for-profit organizations.
Priority service for All entities, including for-profit organizations.
Additional information:
Priority service for members of the Alvin J. Siteman Cancer Center and the Intellectual and Developmental Disabilities Research Center.
Scientific/Technical/Collaborative Contacts:
James Quirk, Ph.D. – 314-362-3875; jdquirk@wustl.edu
Services
- Maintenance of and access to small-animal magnetic resonance imaging scanners
- Assistance with animal procedures and monitoring of small-animal physiologic status during imaging
- Data collection, processing, and analysis
- Consultation regarding pre-clinical research-protocol development
- Support for local and remote data access, analysis, visualization, and archival
- Hands-on instrument training
- Assistance with grant applications and manuscript preparation
Equipment
- Agilent/Varian 11.74-T (500-MHz), 26-cm clear bore, DirectDrive™ MRI scanner
- Bruker 9.4-T (400-MHz), 20-cm clear bore MRI scanner with a mouse brain CryoProbe
- Agilent/Varian 4.7-T (200-MHz), 40-cm clear bore, DirectDrive™ MRI scanner
- MR Solutions 7-T (300 MHz), 17-cm clear bore MRI scanner in ABSL3 facility for infectious disease studies
- Oxford Pulsar FT-NMR Spectrometer 1.4T, 5 cm bore
- Bruker Minispec Relaxometer, 1.4T, 5 cm bore
- Bruker Minispec Relaxometer, 0.47T, 5 cm bore
Pricing
Pricing is subject to core verification
Recharge rates depend on services rendered. Contact the individuals noted above or visit https://www.mir.wustl.edu/research/core-resources/small-animal-magnetic-resonance-facility/faq/ for details regarding usage fees.
AFFILIATIONS
Alvin J. Siteman Cancer Center
Washington University School of Medicine
Barnes-Jewish Hospital