Determine Who Needs a Background Check

A background check is needed if The individual is engaged in the research conducted in the PI’s lab and has access to controlled substances, he or she much obtain an approved DEA background check (including trainees/graduate students) The individual has primary responsibility for the research project and supervisory responsibility for overseeing the safety and security […]

Obtain Controlled Substances

Danforth/Medical School Complete the Controlled Substances Request Form to initiate the purchase of the controlled substances from appropriate campus stockroom. Complete Initial inventory form Keep accurate Aliquot Logs Perform annual inventory as required Dispose or return of unwanted and/or expired controlled substances Promptly report inventory discrepancy, theft and/or loss   An individual researcher registration may […]

Acquire Approval to Begin Working With Controlled Substances (DAF/DCM)

A clinical practice DEA license cannot be used to obtain controlled substances for a research program. Washington University, in accordance with the laws of the State of Missouri and the regulations of the Missouri Bureau of Narcotics & Dangerous Drugs (BNDD), require that an individual maintain separate registrations for their research and clinical programs. You […]

Define “Access to Controlled Substances”

Anyone who is responsible for obtaining, assuring secure storage, managing the initial or annual inventory, completing the aliquot logs, record keeping, distributing controlled substances or a dilution thereof to other approved laboratory personnel, dispensing to an animal or disposing.

Close a Stem Cell Project

February 10, 2017 Send an email to ORIE@wustl.edu referencing the project number Indicate the reason for the closure. For example: No longer using hESCs Lost funding Project completed Leaving Washington University Describe your plans for the hESCs: Destruction Transfer to another Washington University investigator Take to new institution ESCRO will review the terms of the […]

Determine if an MTA is Needed for Stem Cells

February 10, 2017 A Materials Transfer Agreement (MTA) is required for both incoming and outgoing materials. A MTA typically is required when human embryonic stem cells (hESC) are received or shared between Washington University investigators and other academic or industry partners. An MTA or approval/authorization also may be required to obtain hESCs from the WU […]

Submit Stem Cell Project Amendment

February 10, 2017 Complete the ESCRO Amendment (DOC) and email to ORIE@wustl.edu. ESCRO approval covers only the research and specific use of hESC/hPSC/hiPSC lines described in your approved ESCRO application. Any change in the research or hES cell lines approved by ESCRO must be submitted as an Amendment and approved by ESCRO before making the change. […]

Submit Stem Cell Project Annual Renewal

February 10, 2017 ESCRO approval is required annually. You will receive a reminder email approximately six weeks before your expiration date. To continue approval of your ESCRO project: Complete the Renewal Form (DOC) Have the form signed by your department chair Email all documents to ORIE@wustl.edu

Determine Who Can be a PI on an ESCRO Project

February 10, 2017 PIs are usually Washington University faculty members with appointments of instructor or above. However, postdocs who receive their own funding for research using hESC/hPSC (e.g., fellowship award, internal seed grant) will be the PI on the ESCRO application. The research must be overseen by a faculty member, usually the mentor on the […]