The mission of the Washington University DDRCC is to advance research on the pathophysiology of and host-environment interactions in digestive diseases. Tissue imaging and image analysis techniques are essential tools for visualizing the spatial relationships of different cell types, and studying cellular components in the liver and gastrointestinal tract. State-of-the-art histologic, immunohistochemical, tissue imaging and […]
The goal of the core is to provide primary cells and cultured airway epithelial cell preparations from human, mouse and other species for the study of epithelial cells, lung biology and lung diseases. The airway epithelial cell core provides investigators with primary culture preparations of human and mouse airway epithelial cells. We routinely procure human tissues from […]
The Alafi Neuroimaging Laboratory offers state-of-the-art equipment and software for imaging and scanning, and is open to Hope Center investigators and others.
The AMP Core Labs is a CAP/CLIA certified and HIPAA compliant resource that provides services in anatomic pathology.
The Animal Behavior Core (ABC) offers interested investigators a time-efficient, cost-effective opportunity to examine the behavioral consequences of gene mutations as well as assess the effects of specific drugs, experimental manipulations (e.g., neuronal loss), or altered development on behavior in laboratory rodents.
The Animal Model Research Core provides breeding and colony maintenance of rodent models used for nutrition-related research (e.g., animals with lipid abnormalities, atherosclerosis, obesity and diabetes), genotyping, histological analyses, biochemical measurements (plasma lipids, glucose, and hormones) and body composition analyses.
The Animal Models of Joint Injury & Disease Core provides small animal model implementation and functional assessment as an integrated resource. We provide tests of animal behavior, sensitivity, and musculoskeletal function. Rheumatoid arthritis (RA) and osteoarthritis (OA) are highly prevalent and have reached epidemic proportions in the US and worldwide. These joint diseases are characterized […]
The BioBank core provides specimens (blood, resection and endoscopic biopsy specimens, stool) and clinical data collected from patients with gastrointestinal diseases.